TXNRD1 FISH Probe
The TXNRD1 FISH probe is designed to hybridize to the TXNRD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TXNRD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-RE | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-GO | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-GR | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TXNRD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: TXNRD1
Gene Name: Thioredoxin Reductase 1
Chromosome: CHR12: 104609558-104744062
Locus: 12q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TXNRD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TXNRD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping