TWIST1 FISH Probe
The TWIST1 FISH probe is designed to hybridize to the TWIST1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TWIST1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-RE | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-GO | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-GR | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TWIST1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: TWIST1
Gene Name: Twist Family BHLH Transcription Factor 1
Chromosome: CHR7: 19155090-19157295
Locus: 7p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TWIST1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TWIST1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping