TUBA1C FISH Probe
The TUBA1C FISH probe is designed to hybridize to the TUBA1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TUBA1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-RE | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-GO | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-GR | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| TUBA1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: TUBA1A
Gene Name: Tubulin Alpha 1a
Chromosome: CHR12: 49578582-49582861
Locus: 12q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TUBA1C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TUBA1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping