TTR Break Apart FISH Probe
Empire Genomics’ TTR Break Apart FISH Probe is designed to flank the TTR gene and is typically used for detecting TTR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TTRBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TTRBA-20-AQOR | 20 (40 μL) | 200 μL |
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| TTRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| TTRBA-20-GORE | 20 (40 μL) | 200 μL |
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| TTRBA-20-GRGO | 20 (40 μL) | 200 μL |
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| TTRBA-20-GROR | 20 (40 μL) | 200 μL |
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| TTRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| TTRBA-20-REGO | 20 (40 μL) | 200 μL |
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| TTRBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: TTR
Gene Name: Transthyretin
Chromosome: CHR18: 29171729-29178986
Locus: 18q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TTR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TTR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping