TSIX FISH Probe
The TSIX FISH probe is designed to hybridize to the TSIX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TSIX-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TSIX-20-RE | 20 (40 μL) | 200 μL |  |
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| TSIX-20-GO | 20 (40 μL) | 200 μL |  |
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| TSIX-20-GR | 20 (40 μL) | 200 μL |  |
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| TSIX-20-AQ | 20 (40 μL) | 200 μL |  |
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| TSIX-20-DIG | 20 (40 μL) | 200 μL |  |
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| TSIX-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
In mammals, dosage compensation of genes on the X chromosome occurs by X inactivation, which is regulated in cis by the X-inactivation center (XIC) and expression of the XIST non-coding RNA. This gene expresses a non-coding antisense transcript across the 3' end of the XIST locus, and is coexpressed with XIST only from the inactive X chromosome. The mouse ortholog of this locus is required for imprinted X inactivation in extraembryonic tissues and silences Xist through modification of the chromatin structure in the Xist promoter region. In contrast, imprinted X inactivation does not occur in human extraembryonic tissues and transcripts from this locus do not repress XIST expression or affect random X chromosome inactivation in embryonic cells. This transcript is thought to be unspliced and extend over more than 30 kb, but its exact nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TSIX
Gene Name: TSIX Transcript, XIST Antisense RNA
Chromosome: CHRX: 73012039-73049066
Locus: Xq13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TSIX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TSIX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping