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TRNAMI1 FISH Probe

The TRNAMI1 FISH probe is designed to hybridize to the TRNAMI1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TRX-CAT2-1-20-OR  (Standard Design) 20 (40 μL) 200 μL
TRX-CAT2-1-20-RE 20 (40 μL) 200 μL
TRX-CAT2-1-20-GO 20 (40 μL) 200 μL
TRX-CAT2-1-20-GR 20 (40 μL) 200 μL
TRX-CAT2-1-20-AQ 20 (40 μL) 200 μL
TRX-CAT2-1-20-DIG 20 (40 μL) 200 μL
TRX-CAT2-1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Santos and Zasloff (1981) [PubMed 6261953] identified 12 initiator methionine tRNA genes, symbolized tRNA-i(met), in the haploid human genome. Zasloff et al. (1982) [PubMed 6923137] found a variant tRNA-i(met) with a G-to-T transversion in the highly conserved TCGA sequence in loop 4, a sequence position occupied exclusively by a purine (usually G) in almost 200 prokaryotic and eukaryotic tRNAs. One functional consequence of this base substitution is reduction in the rate of processing of the primary transcript of the gene. A second, demonstrated by microinjection into the germinal vesicle of the intact Xenopus laevis oocyte, is blockage of egress from the nucleus. It has been estimated that the human haploid genome contains 1,000 to 2,000 tRNA genes and that there are 50 to 60 chromatographically distinct tRNA species. These observations suggest redundancy of some tRNA genes. The studies of initiator methionine tRNA genes bear out this suspicion.[supplied by OMIM, Sep 2009]

Gene Details

Gene Symbol: TRX-CAT2-1

Gene Name: Transfer RNA-iMet (CAT) 2-1

Chromosome: CHR6: 27777884-27777955

Locus: 6p22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TRNAMI1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TRX-CAT2-1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping