TRMT1 FISH Probe
The TRMT1 FISH probe is designed to hybridize to the TRMT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRMT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-RE | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-GO | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-GR | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TRMT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: TRMT1
Gene Name: TRNA Methyltransferase 1
Chromosome: CHR19: 13215713-13227563
Locus: 19p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TRMT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRMT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping