TRIB2 FISH Probe
The TRIB2 FISH probe is designed to hybridize to the TRIB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TRIB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TRIB2-20-RE | 20 (40 μL) | 200 μL | ||
TRIB2-20-GO | 20 (40 μL) | 200 μL | ||
TRIB2-20-GR | 20 (40 μL) | 200 μL | ||
TRIB2-20-AQ | 20 (40 μL) | 200 μL | ||
TRIB2-20-DIG | 20 (40 μL) | 200 μL | ||
TRIB2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: TRIB2
Gene Name: Tribbles Pseudokinase 2
Chromosome: CHR2: 12856997-12882858
Locus: 2p24.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TRIB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRIB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping