TRAF2 FISH Probe
The TRAF2 FISH probe is designed to hybridize to the TRAF2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRAF2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-RE | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-GO | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-GR | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TRAF2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TRAF2
Gene Name: TNF Receptor Associated Factor 2
Chromosome: CHR9: 139780964-139821067
Locus: 9q34.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TRAF2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRAF2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping