TPO FISH Probe
The TPO FISH probe is designed to hybridize to the TPO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPO-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TPO-20-RE | 20 (40 μL) | 200 μL |  |
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| TPO-20-GO | 20 (40 μL) | 200 μL |  |
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| TPO-20-GR | 20 (40 μL) | 200 μL |  |
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| TPO-20-AQ | 20 (40 μL) | 200 μL |  |
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| TPO-20-DIG | 20 (40 μL) | 200 μL |  |
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| TPO-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: TPO
Gene Name: Thyroid Peroxidase
Chromosome: CHR2: 1417232-1546499
Locus: 2p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TPO FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TPO-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping