TPM1 FISH Probe
The TPM1 FISH probe is designed to hybridize to the TPM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TPM1-20-RE | 20 (40 μL) | 200 μL |  |
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| TPM1-20-GO | 20 (40 μL) | 200 μL |  |
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| TPM1-20-GR | 20 (40 μL) | 200 μL |  |
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| TPM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TPM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TPM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TPM1
Gene Name: Tropomyosin 1
Chromosome: CHR15: 63334837-63364113
Locus: 15q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TPM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TPM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping