TP53I3 FISH Probe
The TP53I3 FISH probe is designed to hybridize to the TP53I3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TP53I3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-RE | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-GO | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-GR | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-AQ | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-DIG | 20 (40 μL) | 200 μL |  |
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| TP53I3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: TP53I3
Gene Name: Tumor Protein P53 Inducible Protein 3
Chromosome: CHR2: 24300302-24308085
Locus: 2p23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TP53I3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TP53I3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping