TP53 FISH Probe
The TP53 FISH probe is designed to hybridize to the TP53 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TP53-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TP53-20-RE | 20 (40 μL) | 200 μL |  |
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| TP53-20-GO | 20 (40 μL) | 200 μL |  |
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| TP53-20-GR | 20 (40 μL) | 200 μL |  |
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| TP53-20-AQ | 20 (40 μL) | 200 μL |  |
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| TP53-20-DIG | 20 (40 μL) | 200 μL |  |
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| TP53-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Gene Details
Gene Symbol: TP53
Gene Name: Tumor Protein P53
Chromosome: CHR17: 7571719-7590863
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TP53 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TP53-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping