TOP3A Break Apart FISH Probe
Empire Genomics’ TOP3A Break Apart FISH Probe is designed to flank the TOP3A gene and is typically used for detecting TOP3A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOP3ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-GORE | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-REGO | 20 (40 μL) | 200 μL |
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| TOP3ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: TOP3A
Gene Name: DNA Topoisomerase III Alpha
Chromosome: CHR17: 18177234-18218321
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TOP3A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TOP3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping