TOP1MT Break Apart FISH Probe
Empire Genomics’ TOP1MT Break Apart FISH Probe is designed to flank the TOP1MT gene and is typically used for detecting TOP1MT rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOP1MTBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-AQOR | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-GOGR | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-GORE | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-GRGO | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-GRRE | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-ORGR | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-REGO | 20 (40 μL) | 200 μL |
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| TOP1MTBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: TOP1MT
Gene Name: DNA Topoisomerase I Mitochondrial
Chromosome: CHR8: 144391527-144417050
Locus: 8q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TOP1MT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TOP1MT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping