TNNT1 Break Apart FISH Probe
Empire Genomics’ TNNT1 Break Apart FISH Probe is designed to flank the TNNT1 gene and is typically used for detecting TNNT1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNNT1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-GORE | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-REGO | 20 (40 μL) | 200 μL |
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| TNNT1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TNNT1
Gene Name: Troponin T1, Slow Skeletal Type
Chromosome: CHR19: 55644160-55660606
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNNT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNNT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping