TNNI2 FISH Probe
The TNNI2 FISH probe is designed to hybridize to the TNNI2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNNI2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-RE | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-GO | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-GR | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TNNI2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: TNNI2
Gene Name: Troponin I2, Fast Skeletal Type
Chromosome: CHR11: 1860232-1862910
Locus: 11p15.5
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNNI2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNNI2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping