TNNI1 FISH Probe
The TNNI1 FISH probe is designed to hybridize to the TNNI1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNNI1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-RE | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-GO | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-GR | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TNNI1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TNNI1
Gene Name: Troponin I1, Slow Skeletal Type
Chromosome: CHR1: 201372894-201390874
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNNI1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNNI1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping