TNFRSF1B FISH Probe
The TNFRSF1B FISH probe is designed to hybridize to the TNFRSF1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNFRSF1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-RE | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-GO | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-GR | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| TNFRSF1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TNFRSF1B
Gene Name: TNF Receptor Superfamily Member 1B
Chromosome: CHR1: 12227059-12269277
Locus: 1p36.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNFRSF1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFRSF1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping