TNFRSF1A Break Apart FISH Probe
Empire Genomics’ TNFRSF1A Break Apart FISH Probe is designed to flank the TNFRSF1A gene and is typically used for detecting TNFRSF1A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNFRSF1ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-GORE | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-REGO | 20 (40 μL) | 200 μL |
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| TNFRSF1ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
Gene Details
Gene Symbol: TNFRSF1A
Gene Name: TNF Receptor Superfamily Member 1A
Chromosome: CHR12: 6437922-6451283
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNFRSF1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFRSF1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping