TNF-C FISH Probe
The TNF-C FISH probe is designed to hybridize to the TNF-C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LTB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LTB-20-RE | 20 (40 μL) | 200 μL |  |
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| LTB-20-GO | 20 (40 μL) | 200 μL |  |
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| LTB-20-GR | 20 (40 μL) | 200 μL |  |
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| LTB-20-AQ | 20 (40 μL) | 200 μL |  |
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| LTB-20-DIG | 20 (40 μL) | 200 μL |  |
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| LTB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LTB
Gene Name: Lymphotoxin Beta
Chromosome: CHR6_mann_hap4: 2891218-2893086
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNF-C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LTB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping