TMPRSS2 FISH Probe
The TMPRSS2 FISH probe is designed to hybridize to the TMPRSS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TMPRSS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-RE | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-GO | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-GR | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-AQ | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-DIG | 20 (40 μL) | 200 μL | ||
TMPRSS2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Details
Gene Symbol: TMPRSS2
Gene Name: Transmembrane Protease, Serine 2
Chromosome: CHR21: 42836477-42880085
Locus: 21q22.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TMPRSS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TMPRSS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping