TMEM2 Break Apart FISH Probe
Empire Genomics’ TMEM2 Break Apart FISH Probe is designed to flank the TMEM2 gene and is typically used for detecting TMEM2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: TMEM2
Gene Name: Transmembrane Protein 2
Chromosome: CHR9: 74298281-74383800
Locus: 9q21.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TMEM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TMEM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping