TLR2 FISH Probe
The TLR2 FISH probe is designed to hybridize to the TLR2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TLR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TLR2-20-RE | 20 (40 μL) | 200 μL |  |
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| TLR2-20-GO | 20 (40 μL) | 200 μL |  |
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| TLR2-20-GR | 20 (40 μL) | 200 μL |  |
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| TLR2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TLR2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TLR2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: TLR2
Gene Name: Toll Like Receptor 2
Chromosome: CHR4: 154605440-154627242
Locus: 4q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TLR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TLR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping