TJP1 Break Apart FISH Probe
Empire Genomics’ TJP1 Break Apart FISH Probe is designed to flank the TJP1 gene and is typically used for detecting TJP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TJP1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TJP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| TJP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TJP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| TJP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TJP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TJP1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| TJP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| TJP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: TJP1
Gene Name: Tight Junction Protein 1
Chromosome: CHR15: 29992356-30114706
Locus: 15q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TJP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TJP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping