TIRAP FISH Probe
The TIRAP FISH probe is designed to hybridize to the TIRAP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TIRAP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-RE | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-GO | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-GR | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-AQ | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-DIG | 20 (40 μL) | 200 μL |  |
|
| TIRAP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TIRAP
Gene Name: TIR Domain Containing Adaptor Protein
Chromosome: CHR11: 126152981-126164828
Locus: 11q24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: TIRAP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TIRAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping