TIMM8A FISH Probe
The TIMM8A FISH probe is designed to hybridize to the TIMM8A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TIMM8A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-RE | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-GO | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-GR | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-AQ | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-DIG | 20 (40 μL) | 200 μL |  |
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| TIMM8A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: TIMM8A
Gene Name: Translocase Of Inner Mitochondrial Membrane 8A
Chromosome: CHRX: 100600643-100603957
Locus: Xq22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TIMM8A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TIMM8A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping