THC FISH Probe
The THC FISH probe is designed to hybridize to the THC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WAS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| WAS-20-RE | 20 (40 μL) | 200 μL |  |
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| WAS-20-GO | 20 (40 μL) | 200 μL |  |
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| WAS-20-GR | 20 (40 μL) | 200 μL |  |
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| WAS-20-AQ | 20 (40 μL) | 200 μL |  |
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| WAS-20-DIG | 20 (40 μL) | 200 μL |  |
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| WAS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: WAS
Gene Name: Wiskott-Aldrich Syndrome
Chromosome: CHRX: 48542185-48549817
Locus: Xp11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: THC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WAS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping