TGFBR2 Break Apart FISH Probe
Empire Genomics’ TGFBR2 Break Apart FISH Probe is designed to flank the TGFBR2 gene and is typically used for detecting TGFBR2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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TGFBR2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-AQOR | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-GOGR | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-GORE | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-GRGO | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-GROR | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-GRRE | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-REGO | 20 (40 μL) | 200 μL | ||
TGFBR2BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: TGFBR2
Gene Name: Transforming Growth Factor Beta Receptor 2
Chromosome: CHR3: 30647993-30735633
Locus: 3p24.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TGFBR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TGFBR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping