TFPI Break Apart FISH Probe
Empire Genomics’ TFPI Break Apart FISH Probe is designed to flank the TFPI gene and is typically used for detecting TFPI rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TFPIBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
TFPIBA-20-AQOR | 20 (40 μL) | 200 μL | ||
TFPIBA-20-GOGR | 20 (40 μL) | 200 μL | ||
TFPIBA-20-GORE | 20 (40 μL) | 200 μL | ||
TFPIBA-20-GRGO | 20 (40 μL) | 200 μL | ||
TFPIBA-20-GRRE | 20 (40 μL) | 200 μL | ||
TFPIBA-20-ORGR | 20 (40 μL) | 200 μL | ||
TFPIBA-20-REGO | 20 (40 μL) | 200 μL | ||
TFPIBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: TFPI
Gene Name: Tissue Factor Pathway Inhibitor
Chromosome: CHR2: 188328957-188419219
Locus: 2q32.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TFPI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TFPI-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping