TERC FISH Probe
The TERC FISH probe is designed to hybridize to the TERC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TERC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TERC-20-RE | 20 (40 μL) | 200 μL |  |
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| TERC-20-GO | 20 (40 μL) | 200 μL |  |
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| TERC-20-GR | 20 (40 μL) | 200 μL |  |
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| TERC-20-AQ | 20 (40 μL) | 200 μL |  |
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| TERC-20-DIG | 20 (40 μL) | 200 μL |  |
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| TERC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component, encoded by this gene, that serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Mutations in this gene cause autosomal dominant dyskeratosis congenita, and may also be associated with some cases of aplastic anemia. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TERC
Gene Name: Telomerase RNA Component
Chromosome: CHR3: 169482397-169482848
Locus: 3q26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TERC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TERC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping