TDP1 FISH Probe
The TDP1 FISH probe is designed to hybridize to the TDP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TDP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TDP1-20-RE | 20 (40 μL) | 200 μL |  |
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| TDP1-20-GO | 20 (40 μL) | 200 μL |  |
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| TDP1-20-GR | 20 (40 μL) | 200 μL |  |
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| TDP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TDP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TDP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: TDP1
Gene Name: Tyrosyl-DNA Phosphodiesterase 1
Chromosome: CHR14: 90422245-90511108
Locus: 14q32.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TDP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TDP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping