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TCF3 FISH Probe

The TCF3 FISH probe is designed to hybridize to the TCF3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
TCF3-20-OR  (Standard Design) 20 (40 μL) 200 μL
TCF3-20-RE 20 (40 μL) 200 μL
TCF3-20-GO 20 (40 μL) 200 μL
TCF3-20-GR 20 (40 μL) 200 μL
TCF3-20-AQ 20 (40 μL) 200 μL
TCF3-20-DIG 20 (40 μL) 200 μL
TCF3-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol: TCF3

Gene Name: Transcription Factor 3

Chromosome: CHR19: 1609288-1652328

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: TCF3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TCF3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping