TAP2 FISH Probe
The TAP2 FISH probe is designed to hybridize to the TAP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| TAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| TAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| TAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: TAP2
Gene Name: Transporter 2, ATP Binding Cassette Subfamily B Member
Chromosome: CHR6_qbl_hap6: 4021716-4038655
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TAP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping