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TAB2 FISH Probe

The TAB2 FISH probe is designed to hybridize to the TAB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
TAB2-20-OR  (Standard Design) 20 (40 μL) 200 μL
TAB2-20-RE 20 (40 μL) 200 μL
TAB2-20-GO 20 (40 μL) 200 μL
TAB2-20-GR 20 (40 μL) 200 μL
TAB2-20-AQ 20 (40 μL) 200 μL
TAB2-20-DIG 20 (40 μL) 200 μL
TAB2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Gene Details

Gene Symbol: TAB2

Gene Name: TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2

Chromosome: CHR6: 149639435-149732747

Locus: 6q25.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TAB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TAB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping