T14 FISH Probe
The T14 FISH probe is designed to hybridize to the T14 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CD27-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CD27-20-RE | 20 (40 μL) | 200 μL | ||
CD27-20-GO | 20 (40 μL) | 200 μL | ||
CD27-20-GR | 20 (40 μL) | 200 μL | ||
CD27-20-AQ | 20 (40 μL) | 200 μL | ||
CD27-20-DIG | 20 (40 μL) | 200 μL | ||
CD27-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CD27
Gene Name: CD27 Molecule
Chromosome: CHR12: 6554050-6560884
Locus: 12p13.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: T14 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD27-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping