SYNGAP1 Break Apart FISH Probe
Empire Genomics’ SYNGAP1 Break Apart FISH Probe is designed to flank the SYNGAP1 gene and is typically used for detecting SYNGAP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SYNGAP1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| SYNGAP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Details
Gene Symbol: SYNGAP1
Gene Name: Synaptic Ras GTPase Activating Protein 1
Chromosome: CHR6: 33387846-33421466
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SYNGAP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SYNGAP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping