STRADB Break Apart FISH Probe
Empire Genomics’ STRADB Break Apart FISH Probe is designed to flank the STRADB gene and is typically used for detecting STRADB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STRADBBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STRADBBA-20-AQOR | 20 (40 μL) | 200 μL |
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| STRADBBA-20-GOGR | 20 (40 μL) | 200 μL |
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| STRADBBA-20-GORE | 20 (40 μL) | 200 μL |
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| STRADBBA-20-GRGO | 20 (40 μL) | 200 μL |
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| STRADBBA-20-GROR | 20 (40 μL) | 200 μL |
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| STRADBBA-20-GRRE | 20 (40 μL) | 200 μL |
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| STRADBBA-20-REGO | 20 (40 μL) | 200 μL |
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| STRADBBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: STRADB
Gene Name: STE20-related Kinase Adaptor Beta
Chromosome: CHR2: 202316391-202345574
Locus: 2q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: STRADB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STRADB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping