STAT5B FISH Probe
The STAT5B FISH probe is designed to hybridize to the STAT5B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAT5B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-RE | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-GO | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-GR | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-AQ | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-DIG | 20 (40 μL) | 200 μL |  |
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| STAT5B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: STAT5B
Gene Name: Signal Transducer And Activator Of Transcription 5B
Chromosome: CHR17: 40351194-40428424
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: STAT5B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STAT5B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping