STAT3 FISH Probe
The STAT3 FISH probe is designed to hybridize to the STAT3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAT3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-RE | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-GO | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-GR | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-AQ | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-DIG | 20 (40 μL) | 200 μL |  |
|
| STAT3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: STAT3
Gene Name: Signal Transducer And Activator Of Transcription 3
Chromosome: CHR17: 40465342-40540513
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: STAT3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STAT3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping