STAP1 FISH Probe
The STAP1 FISH probe is designed to hybridize to the STAP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
STAP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
STAP1-20-RE | 20 (40 μL) | 200 μL | ||
STAP1-20-GO | 20 (40 μL) | 200 μL | ||
STAP1-20-GR | 20 (40 μL) | 200 μL | ||
STAP1-20-AQ | 20 (40 μL) | 200 μL | ||
STAP1-20-DIG | 20 (40 μL) | 200 μL | ||
STAP1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: STAP1
Gene Name: Signal Transducing Adaptor Family Member 1
Chromosome: CHR4: 68424445-68472616
Locus: 4q13.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: STAP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STAP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping