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SREBF1 FISH Probe

The SREBF1 FISH probe is designed to hybridize to the SREBF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SREBF1-20-OR  (Standard Design) 20 (40 μL) 200 μL
SREBF1-20-RE 20 (40 μL) 200 μL
SREBF1-20-GO 20 (40 μL) 200 μL
SREBF1-20-GR 20 (40 μL) 200 μL
SREBF1-20-AQ 20 (40 μL) 200 μL
SREBF1-20-DIG 20 (40 μL) 200 μL
SREBF1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017]

Gene Details

Gene Symbol: SREBF1

Gene Name: Sterol Regulatory Element Binding Transcription Factor 1

Chromosome: CHR17: 17714662-17740325

Locus: 17p11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: SREBF1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SREBF1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping