SPN FISH Probe
The SPN FISH probe is designed to hybridize to the SPN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPN-20-RE | 20 (40 μL) | 200 μL |  |
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| SPN-20-GO | 20 (40 μL) | 200 μL |  |
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| SPN-20-GR | 20 (40 μL) | 200 μL |  |
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| SPN-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPN-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: SPN
Gene Name: Sialophorin
Chromosome: CHR16: 29674299-29681823
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping