SPGY FISH Probe
The SPGY FISH probe is designed to hybridize to the SPGY gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAZ1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-RE | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-GO | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-GR | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DAZ1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DAZ1
Gene Name: Deleted In Azoospermia 1
Chromosome: CHRY: 25275501-25345239
Locus: Yq11.223
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPGY FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DAZ1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping