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SPG21 FISH Probe

The SPG21 FISH probe is designed to hybridize to the SPG21 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
SPG21-20-OR  (Standard Design) 20 (40 μL) 200 μL
SPG21-20-RE 20 (40 μL) 200 μL
SPG21-20-GO 20 (40 μL) 200 μL
SPG21-20-GR 20 (40 μL) 200 μL
SPG21-20-AQ 20 (40 μL) 200 μL
SPG21-20-DIG 20 (40 μL) 200 μL
SPG21-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Gene Details

Gene Symbol: SPG21

Gene Name: SPG21, Maspardin

Chromosome: CHR15: 65255362-65282251

Locus: 15q22.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: SPG21 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SPG21-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping