SPG21 FISH Probe
The SPG21 FISH probe is designed to hybridize to the SPG21 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPG21-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPG21-20-RE | 20 (40 μL) | 200 μL |  |
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| SPG21-20-GO | 20 (40 μL) | 200 μL |  |
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| SPG21-20-GR | 20 (40 μL) | 200 μL |  |
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| SPG21-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPG21-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPG21-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Gene Details
Gene Symbol: SPG21
Gene Name: SPG21, Maspardin
Chromosome: CHR15: 65255362-65282251
Locus: 15q22.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPG21 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPG21-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping