SPEN Break Apart FISH Probe
Empire Genomics’ SPEN Break Apart FISH Probe is designed to flank the SPEN gene and is typically used for detecting SPEN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPENBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPENBA-20-AQOR | 20 (40 μL) | 200 μL |
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| SPENBA-20-GOGR | 20 (40 μL) | 200 μL |
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| SPENBA-20-GORE | 20 (40 μL) | 200 μL |
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| SPENBA-20-GRGO | 20 (40 μL) | 200 μL |
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| SPENBA-20-GROR | 20 (40 μL) | 200 μL |
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| SPENBA-20-GRRE | 20 (40 μL) | 200 μL |
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| SPENBA-20-REGO | 20 (40 μL) | 200 μL |
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| SPENBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SPEN
Gene Name: Spen Family Transcriptional Repressor
Chromosome: CHR1: 16174358-16266950
Locus: 1p36.21-p36.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPEN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPEN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping