SPEN FISH Probe
The SPEN FISH probe is designed to hybridize to the SPEN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPEN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPEN-20-RE | 20 (40 μL) | 200 μL |  |
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| SPEN-20-GO | 20 (40 μL) | 200 μL |  |
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| SPEN-20-GR | 20 (40 μL) | 200 μL |  |
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| SPEN-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPEN-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPEN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SPEN
Gene Name: Spen Family Transcriptional Repressor
Chromosome: CHR1: 16174358-16266950
Locus: 1p36.21-p36.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPEN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPEN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping