SPATA18 FISH Probe
The SPATA18 FISH probe is designed to hybridize to the SPATA18 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPATA18-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-RE | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-GO | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-GR | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPATA18-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Details
Gene Symbol: SPATA18
Gene Name: Spermatogenesis Associated 18
Chromosome: CHR4: 52917592-52963458
Locus: 4q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPATA18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPATA18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping