SPANXA1 Break Apart FISH Probe
Empire Genomics’ SPANXA1 Break Apart FISH Probe is designed to flank the SPANXA1 gene and is typically used for detecting SPANXA1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPANXA1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SPANXA1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SPANXA1
Gene Name: Sperm Protein Associated With The Nucleus, X-linked, Family Member A1
Chromosome: CHRX: 140677858-140678889
Locus: Xq27.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SPANXA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPANXA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping