SPAG6 FISH Probe
The SPAG6 FISH probe is designed to hybridize to the SPAG6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPAG6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-RE | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-GO | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-GR | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPAG6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: SPAG6
Gene Name: Sperm Associated Antigen 6
Chromosome: CHR10: 22634398-22706539
Locus: 10p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPAG6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPAG6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping